Vaccines with chimeric protein comprising gamma-interferon and leukotoxin derived from pasteurella haemolytica
US6096320A · kind A · utility
4Cited by
18References
13Claims
0Family size
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Key dates
| Filing date | Oct 20, 1997 |
| Grant date | Aug 1, 2000 |
| Priority date | — |
| Expiry date | Oct 20, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of an RTX cytotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.