Retroviral vectors
US6096538A · kind A · utility
32Cited by
6References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 1997 |
| Grant date | Aug 1, 2000 |
| Priority date | — |
| Expiry date | Nov 19, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A DNA construct is disclosed which comprises a packagable retroviral genome operably linked to a first promotor, wherein the retroviral genome comprises a 5' long terminal repeat (5' LTR) which includes sequences encoding R and U3 regions and 3' long terminal repeat (3' LTR) which includes sequences encoding R and U3 regions, and wherein at least said R regions of the 5' LTR and 3' LTR are identical to each other and are different from those of the retrovirus on which the retroviral genome is based. The DNA constructs are useful in the production of packaged retroviruses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.