Patent · US Expired

Multimeric antiviral agent

US6096862A · kind A · utility

6Cited by

43References

10Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Jeffrey Greve · Branford, US
Alan McClelland · Tervuren, BE

Key dates

Filing date	Oct 4, 1994
Grant date	Aug 1, 2000
Priority date	—
Expiry date	Oct 4, 2014

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Multimeric antiviral agents comprising two or more monomers selected from the group consisting of monomers of transmembrane intracellular adhesion molecule-1 (tmICAM-1) and truncated intercellular adhesion molecule-1 (tICAMs), with the proviso that when said multimer is a dimer said monomers cannot both be tmICAM-1, wherein each of said monomers comprises the human rhinovirus (HRV) binding site and retains the ability to bind to HRV and reduce infectivity thereof, and wherein said multimeric antiviral agent mimics the multimeric configuration of tmICAM-1 and exhibits enhanced binding to said HRV relative to at least one of the constituent monomers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.