Detection of retroviral subtypes based upon envelope specific sequences
US6100034A · kind A · utility
3Cited by
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27Claims
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Key dates
| Filing date | Jul 7, 1998 |
| Grant date | Aug 8, 2000 |
| Priority date | — |
| Expiry date | Jul 7, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/10022
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is based upon the finding that porcine endogenous retroviruses exist in two different subtypes, which we have termed PERV-A and PERV-B. The differences are reflected in sequence divergence in the envelope genes, and these differences may be used to provide nucleic acid and antibody probes which can distinguish between the two subtypes. This allows patterns of subtype transmission between cells, particularly porcine to human cells, to be monitored.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.