Modified acyl-ACP desaturase
US6100091A · kind A · utility
4Cited by
2References
58Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 25, 1999 |
| Grant date | Aug 8, 2000 |
| Priority date | — |
| Expiry date | Mar 25, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a methods for modifying the chain length and double bond positional specificities of a soluble plant fatty acid desaturase. More specifically, the method involves modifying amino acid contact residues in the substrate binding channel of the soluble fatty acid desaturase which contact the fatty acid. Specifically disclosed is the modification of an acyl-ACP desaturase. Amino acid contact residues which lie within the substrate binding channel are identified, and subsequently replaced with different residues to effect the modification of activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.