Patent · US Expired

Combination therapy to treat osteoporosis-polyphosphonates and estrogen agonists

US6100301A · kind A · utility

1Cited by
2References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 5, 1998
Grant dateAug 8, 2000
Priority date
Expiry dateJun 5, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/29
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides novel methods of treating or preventing osteoporosis comprising administering to a mammal in need of such treatment an effective amount of a compound of formula I ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different provided that, when R.sup.1 and R.sup.2 are the same, each is a methyl or ethyl group, and, when R.sup.1 and R.sup.2 are different, one of them is a methyl or ethyl group and the other is hydrogen or a benzyl group; or a pharmaceutically acceptable salt thereof; together with a bone resorption inhibiting polyphosphonate, or with parathyroid hormone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.