Process for the preparation of liposomes without the use of an organic solvent
US6103259A · kind A · utility
6Cited by
1References
19Claims
0Family size
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Key dates
| Filing date | Apr 30, 1998 |
| Grant date | Aug 15, 2000 |
| Priority date | — |
| Expiry date | Apr 30, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Multilamellar lipid vesicles are prepared by a two-step method. In the first step, a sterol is completely dissolved in a mixture comprising an aqueous solvent and a surfactant. In the second step, a lipid surfactant is added to a solution resulting from the first step, to prepare a homogeneous lamellar liquid crystal phase or a liquid crystal phase suspension in water. The liquid crystal phase or liquid crystal phase suspension can then be converted into multilamellar lipid vesicles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.