Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues
US6103266A · kind A · utility
Inventors
Key dates
| Filing date | Apr 22, 1998 |
| Grant date | Aug 15, 2000 |
| Priority date | — |
| Expiry date | Apr 22, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/7015
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a non water-soluble pharmaceutical carrier gel which adheres to mucosal surfaces and body tissues upon application and forms a film, providing protection and delivery of pharmaceutical to the site of application, surrounding body tissues, and bodily fluids. The gel comprises a volatile or diffusing nonaqueous solvent and at least one non-water-soluble alkyl cellulose or hydroxyalkyl cellulose. A bioadhesive polymer may also be added. The gel provides an effective residence time with ease of use. The residence time may be adjusted by adding a component which acts to adjust the kinetics of erodability of the carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.