Miniaturized cell array methods and apparatus for cell-based screening
US6103479A · kind A · utility
302Cited by
27References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 29, 1997 |
| Grant date | Aug 15, 2000 |
| Priority date | — |
| Expiry date | May 29, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/1497
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention discloses devices and methods of performing high throughput screening of the physiological response of cells to biologically active compounds and methods of combining high-throughput with high-content spatial information at the cellular and subcellular level as well as temporal information about changes in physiological, biochemical and molecular activities. The present invention allows multiple types of cell interactions to be studied simultaneously by combining multicolor luminescence reading, microfluidic delivery, and environmental control of living cells in non-uniform micro-patterned arrays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.