Modified glucose dehydrogenase
US6103509A · kind A · utility
164Cited by
1References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 4, 1997 |
| Grant date | Aug 15, 2000 |
| Priority date | — |
| Expiry date | Sep 4, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/0006
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides a modified pyrrolo-quinoline quinone glucose dehydrogenase (PQQGDH) enzyme protein which is modified to have a substrate specificity to glucose. The modified PQQGDH of the invention exhibits a high substrate specificity compared to the wild type PQQGDH, thus is useful in determining glucose concentration in clinical assays and food analyses. A gene coding for the modified PQQGDH and a glucose sensor comprising the modified PQQGDH are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.