Patent · US Expired

Quinazolines

US6103728A · kind A · utility

43Cited by
12References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 28, 1997
Grant dateAug 15, 2000
Priority date
Expiry dateFeb 28, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Molecules that are capable of modulating tyrosine signal transduction to prevent and treat cell proliferative disorders or cell differentiation disorders with particular tyrosine kinases by inhibiting one or more abnormal tyrosine kinase activities. These compounds have the structural formula ##STR1## wherein R1-R10 are disclosed in the specification. The specification also provides pharmaceutical compositions and methods for inhibiting cell proliferation or differentiation and related disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.