Patent · US Expired

Lysis chamber for use in an assay device

US6106779A · kind A · utility

55Cited by
12References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 2, 1997
Grant dateAug 22, 2000
Priority date
Expiry dateOct 2, 2017

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/117497
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A lysis chamber of an assay device capable of producing lysis of cells in a sample fluid such as whole blood, said chamber comprising a surface which contacts the sample fluid when the sample fluid is placed into the assay device; and a lytic material immobilized on the surface, whereby cells of the sample fluid are lysed when they contact the lytic material. The chamber can delimit a capillary space, and lytic material can be saponin or a detergent. Methods employing devices comprising such chambers can assay for whole blood amounts of cyclosporin or hemoglobin A1c.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.