Non-crystalline cefuroxime axetil solid dispersant, process for preparing same and composition for oral administration thereof
US6107290A · kind A · utility
8Cited by
3References
10Claims
0Family size
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Key dates
| Filing date | Sep 16, 1999 |
| Grant date | Aug 22, 2000 |
| Priority date | — |
| Expiry date | Sep 16, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-crystalline cefuroxime axetil solid dispersant showing no absorption peak on a Differential Scanning Calorimetry scan is prepared by (a) dissolving cefuroxime axetil and a surfactant in an organic solvent; (b) suspending a water-insoluble inorganic carrier in the resulting solution; and (c) drying the resulting suspension to remove the organic solvent, said solid dispersant having an improved bioavailability and stability of cefuroxime axetil and being useful for the preparation of a pharmaceutical composition for oral administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.