Dopamine receptor antagonists
US6107313A · kind A · utility
1Cited by
4References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 2, 1998 |
| Grant date | Aug 22, 2000 |
| Priority date | — |
| Expiry date | Oct 2, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides a novel class of oxadiazolyl piperidines which exhibit a high binding affinity for dopamine ligands. The compounds of the invention display selectivity for the dopamine D.sub.4 receptor over the dopamine D.sub.2 receptor. Preferably, these compounds act as dopamine antagonists, which are useful in the treatment of psychotic disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.