Locus control subregions conferring integration-site independent transgene expression abstract of the disclosure
US6110666A · kind A · utility
7Cited by
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3Claims
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Assignee
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Aug 29, 2000 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention encompasses a locus control subregion that possesses chromatin opening domain activity, the activity conferring reproducible activation of tissue-specific expression on a linked transgene to a non-physiological level when the transgene is integrated in single copy in the genome of a host cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.