Aromatic amine derivatives
US6110945A · kind A · utility
23Cited by
4References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 2, 1999 |
| Grant date | Aug 29, 2000 |
| Priority date | — |
| Expiry date | Jun 2, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Aromatic amines of formula (1) are described: ##STR1## wherein Az is an optionally substituted monocyclic six-membered nitrogen-containing aromatic group; PA0 L.sup.1 is a linker atom or group; PA0 R is a carboxylic acid or a derivative thereof; PA0 and R.sup.5 is a group --L.sup.2 (CH.sub.2).sub.t R.sup.6 in which L.sup.2 is a --N(R.sup.7)CO-- or --N(R.sup.7)CS-- group. The compounds are able to inhibit the binding of .alpha..sub.4 integrins to their ligands and are of use in the prophylaxis and treatment of immune or inflammatory disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.