Process for scavenging thiols
US6114537A · kind A · utility
10Cited by
0References
5Claims
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Key dates
| Filing date | Feb 21, 1997 |
| Grant date | Sep 5, 2000 |
| Priority date | — |
| Expiry date | Feb 21, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C319/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Thiols are trapped, and converted to disulfide compounds, by a process of reacting them with compounds containing a 1,2,4-thiadiazole ring structure carrying a substituent at position 3 of the thiadiazole ring, and being unsubstituted at position N-2. The process is useful pharmacologically, in inhibiting certain thiol-containing enzymes such as H.sup.+ /K.sup.+ -ATPase (the proton pump), and industrially, in selective removal of thiol compounds from gas or liquid mixtures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.