Process for quantifying glycosaminoglycans in antithrombin III-containing solutions

US6117647A · kind A · utility

Assignee

• Aventis Behring GmbH · DE

Inventors

• Jürgen Römisch · Marburg, DE
• Harald Stauss · Steffenberg, DE

Key dates

• Filing date: Aug 13, 1997
• Grant date: Sep 12, 2000
• Expiry date: Aug 13, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/255
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A process for determining glycosaminoglycans in antithrombin III (ATIII)-containing solutions by increasing the ionic strength of the AT III-containing solution until the interaction between AT III and glycosaminoglycans is prevented, removing the AT III which has been released from the glycosaminoglycans from the solution, and desalting and determining the glycosaminoglycan which has remained in the solution.