Method for producing an adapted virus population from an African green monkey kidney cell line
US6117667A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jun 21, 1999 |
| Grant date | Sep 12, 2000 |
| Priority date | — |
| Expiry date | Jun 21, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention described herein provides a method for selecting a novel African Green monkey kidney (AGMK) cell substrate, its cultivation and serial passage and its subsequent characterization. The invention provides a method for the use of the cell substrate in the isolation, growth and serial passage of a large number of viruses, particularly rotaviruses, enteroviruses, respiratory viruses and hepatitis A virus. The invention provides a method for the utilization of this AGMK cell substrate for the production of live and killed virus vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.