CS-1 peptidomimetics, compositions and methods of using the same
US6117840A · kind A · utility
3Cited by
5References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 14, 1997 |
| Grant date | Sep 12, 2000 |
| Priority date | — |
| Expiry date | Apr 14, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention contemplates a peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory peptide are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.