Method of relieving chronic inflammation by using 5-alkylsulfonylsalicylanilides

US6117859A · kind A · utility

Assignee

• The Research Foundation of the State University of New York · US

Inventors

• Richard T. Evans · East Amherst, US
• Robert A. Coburn · Williamsville, US
• Robert J. Genco · Buffalo, US
• Joseph A. Dunn · Amherst, US

Key dates

• Filing date: Sep 28, 1999
• Grant date: Sep 12, 2000
• Expiry date: Sep 28, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/1075
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of treating chronic inflammation in a mammal is disclosed which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of the following formula: ##STR1## wherein Z is a substituted phenyl ring, R is an alkylsulfonyl group of 1-20 carbon atoms, and X is selected from the group consisting of --CN, --NO.sub.2, --H, halogen, lower alkyl and lower haloalkyl.