Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6117911A · kind A · utility
144Cited by
83References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1998 |
| Grant date | Sep 12, 2000 |
| Priority date | — |
| Expiry date | Apr 9, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/323
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.