Liposome-entrapped polynucleotide composition and method
US6120798A · kind A · utility
39Cited by
2References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 23, 1998 |
| Grant date | Sep 19, 2000 |
| Priority date | — |
| Expiry date | Jun 23, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A liposome composition for administration of a polynucleotide and a method of preparing the composition are described. The liposomes in the suspension are composed predominantly of liposomes having a bilayer membrane formed of cationic vesicle-forming lipids and neutral vesicle forming lipids. The polynucleotide is entrapped in the central core of the liposomes and is localized predominantly on the inner surface of the core.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.