Method of producing multi-layer medicaments in solid form for oral or rectal administration

US6120802A · kind A · utility

Assignee

• BASF SE

Inventors

• Jorg Breitenbach · Mannheim, DE
• Axel Paul Hartl · Dirmstein, DE
• Jurgen Hofmann · Spalt, DE
• Joerg Rosenberg · Ellerstadt, DE
• Michael Schiessl · Altrip, DE
• Hans D. Zettler · Havelsee, DE

Key dates

• Filing date: Apr 15, 1998
• Grant date: Sep 19, 2000
• Expiry date: Apr 15, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61J2200/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.