Non-aggregated fluorescent conjugates and the process for their preparation
US6120987A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 10, 1998 |
| Grant date | Sep 19, 2000 |
| Priority date | — |
| Expiry date | Jun 10, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/80
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a process for the preparation of a fluorescent conjugate between a carrier molecule possessing at least one amino, hydroxyl, carboxyl and/or sulfhydryl group and a fluorophoric reagent possessing at least one functional group capable of reacting with said amino, hydroxyl, carboxyl and/or sulfhydryl group(s), which consists in bringing said carrier molecule and said fluorophoric reagent into contact with an aqueous solution of a water-soluble macrocycle. The invention further relates to the conjugates obtained by this process and to their use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.