Epiligrin, an epithelial ligand for integrins
US6120991A · kind A · utility
10Cited by
3References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1996 |
| Grant date | Sep 19, 2000 |
| Priority date | — |
| Expiry date | Feb 22, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Nucleic acid sequences are disclosed encoding an E170 epithelial ligand and capable of hybridizing under stringent conditions to the nucleotide sequences derived from cDNA clones shown in the figure. Also disclosed are vectors containing the nucleic acid sequences, and cells transformed with the vectors. Methods are given for purifying and utilizing epiligrin, an epithelial glycoprotein complex, and its component glycoproteins, and for raising antibodies against components of this complex. Assay methods are further provided for identification of functional epiligrin in tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.