Anticoagulant peptide aldehyde derivatives
US6121241A · kind A · utility
0Cited by
1References
9Claims
0Family size
Assignee
Inventors
- Sandor Bajusz
- Attila Juhasz
- Eva Barabas
- Andras Feher
- Gabriella Szabo
- Erzsebet Szell nee Hasenohrl
- Iren Veghelyi nee Fauszt
- Emilia Lavich nee Oszko
- Eva Kaszas
- Jozsef Lango
- Imre Moravcsik
- Agnes Szeker nee Peszeky
- Zsuzsanna Taschler nee Pasztor
- Gabor Toth
- Zsuzsanna Mohai nee Nagy
- Anna Maria Szalkay nee Hollosi
- Klara Makk nee Ocskay
Key dates
| Filing date | Apr 2, 1999 |
| Grant date | Sep 19, 2000 |
| Priority date | — |
| Expiry date | Apr 2, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to peptide aldehyde derivatives of formula (I): D-Xaa-Pro-Arg-H, wherein Xaa represent a 2-cycloheptyl-2-hydroxyacetyl or 2-cyclopentyl-2-hydroxyacetyl group, Pro represents an L-prolyl residue and Arg represents an L-arginyl residue, their acid-additon salts formed with an organic or inorganic acid and pharmaceutical compositions containing the same. The compounds of formula (I) of the invention have therapeutic, particularly anticoagulant, antiplatelet and antithrombotic properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.