Patent · US Expired

N-aryloxyethyl-indoly-alkylamines for the treatment of depression

US6121307A · kind A · utility

3Cited by
4References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 7, 1999
Grant dateSep 19, 2000
Priority date
Expiry dateApr 7, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds useful for alleviating symptoms of depression are provided which have the following formula: wherein: PA1 R.sub.1 is hydrogen, lower alkyl or aryl; PA1 R.sub.2 is hydrogen, lower alkyl, phenyl or substituted phenyl; PA1 X and Y are each, independently, hydrogen, lower alkyl, lower alkoxy, or halogen, or together combine with the carbon atoms to which they are attached to complete a pyranyl, dihydrofuranyl, furanyl, or dioxanyl, group; PA1 Z is hydrogen, halogen or lower alkoxy; with the proviso that when X, Y or Z represent lower alkoxy, they are not present at the ortho position; PA1 W is hydrogen, halogen, lower alkyl, cyano or a trifluoromethyl group; and PA1 n is 2-5; or PA1 pharmaceutically acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.