Preparation of salts of ascorbyl 2-phosphoric esters

US6121464A · kind A · utility

Inventors

• Andreas Böttcher · Mettmann, DE
• Hans Gurski · Lambsheim, DE

Key dates

• Filing date: Jul 13, 1999
• Grant date: Sep 19, 2000
• Expiry date: Jul 13, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/65515
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for preparing salts of ascorbyl 2-phosphoric esters of the formula I, ##STR1## where the variables have the following meanings: M is sodium, potassium, magnesium, aluminum; ##STR2## k.sym. is the valence and m=equivalents, where the product of k.multidot.m can be from 3 to 5, comprises PA1 a) dissolving calcium L-ascorbate-2-phosphate in an aqueous solution of ascorbyl 2-phosphoric esters at a pH of from 0.5 to 4, PA1 b) removing the calcium ions from the resulting solution, PA1 c) adjusting the pH of the solution which remains to from 7 to 11 by means of sodium, potassium, magnesium or aluminum salts and PA1 d) isolating the salts of the ascorbyl 2-phosphoric ester of the formula I.