Patent · US Expired

Process for production drospirenone and intermediate products of the process

US6121465A · kind A · utility

14Cited by
3References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 11, 1999
Grant dateSep 19, 2000
Priority date
Expiry dateFeb 11, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J53/008
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Process for the production of drospirenone (6.beta., 7.beta.; 15.beta., 16.beta.-dimethylene-3-oxo-17.alpha.-pregn-4-ene-21, 17-carbolactone, DRSP) (1) and 7.alpha.-(3-hydroxy-1-propyl)-6.beta., 7.beta.; 15.beta., 16.beta.-dimethylene-5.beta.-androstane-3.beta., 5, 17.beta.-triol (ZK 92836) and 6.beta., 7.beta.; 15.beta., 16.beta.-dimethylene-5.beta.-hydroxy-3-oxo-17.alpha.-androstane-21, 17-carbolactone (ZK 90965) as intermediate products of the process. ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.