Patent · US Expired

Pharmaceutically enhanced low-energy radiosurgery

US6125295A · kind A · utility

19Cited by
4References
35Claims
0Family size

Inventors

Key dates

Filing dateAug 27, 1998
Grant dateSep 26, 2000
Priority date
Expiry dateAug 27, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61N2005/1098
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Contrast agents developed specifically for x-ray diagnostics provide dose-enhanced radiotherapy and radiosurgery. The presence of heavy elements from these contrast agents, even small quantities, leads to a major dose increase in target tissue. When combined with in vivo calibration of the amount of contrast agent, the procedure is quick, accurate, and safe. The technique can also be used in combination with other techniques, such as focused x-rays, to achieve further enhancement of therapeutic ratio. Through optimization of the equipment it is possible to achieve very large ratios of dose in target to dose in healthy tissue up to 10:1.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.