Screening assays to identify therapeutic agents for amyloidosis
US6126918A · kind A · utility
20Cited by
1References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 22, 1996 |
| Grant date | Oct 3, 2000 |
| Priority date | — |
| Expiry date | Aug 22, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Therapeutical and diagnostic agents for amyloidosis comprise molecules that inhibit the binding of serum amyloid P component to amyloid fibrils or analogues or homologues of the amyloid binding site on serum amyloid P component. The resolution of the complete three dimensional structure of serum amyloid P component enables inhibitors, binding site analogues and homologues to be designed by computer-aided molecular modelling.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.