Patent · US Expired

Method for diagnosing glioma associated with structural alterations of the EGF receptor gene in human tumors

US6127126A · kind A · utility

23Cited by

4References

6Claims

0Family size

Assignees

THE JOHNS HOPKINS UNIVERSITY · US
Duke University · US

Inventors

Bert Vogelstein · Baltimore, US
Darell Bigner · Mebane, US

Key dates

Filing date	Mar 9, 1999
Grant date	Oct 3, 2000
Priority date	—
Expiry date	Mar 9, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Deletions in the EGF-R gene are found in many gliomas, breast tumors, and lung tumors. A particular truncated EGFR protein has been found in many tumors and provides diagnostic and therapeutic modalities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.