Vinca alkaloid antimitotic halogenated derivatives
US6127377A · kind A · utility
13Cited by
0References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 7, 1999 |
| Grant date | Oct 3, 2000 |
| Priority date | — |
| Expiry date | Oct 7, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns novel halogenated derivatives of the vinblastine and vinorelbine family, corresponding to general formula (I) and their therapeutically acceptable salts. The invention also concerns the application of these compounds in therapy and their method of preparation. The invention further concerns a novel method for preparing vinflunine or 20',20'-difluoro-3',4'-dihydrovinorelbine, of formula (a). ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.