Patent · US Expired

Taxane hydroxy monoacylation method

US6127555A · kind A · utility

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20Claims
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Assignee

Inventors

Key dates

Filing dateMay 5, 1999
Grant dateOct 3, 2000
Priority date
Expiry dateMay 5, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D305/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A process for selective monoacylation of 10-deacetylbaccatin III, or a derivative thereof in positions C-2 and C-4 possessing free hydroxyl groups in positions C-7 and C-10, using a methyleneiminium salt.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.