Clean generation of a perfluoroaryl grignard reagent

US6129863A · kind A · utility

Assignee

• ALBEMARLE CORPORATION · US

Inventors

• John Y. Lee · Baton Rouge, US
• David W. Owens · Baton Rouge, US
• Charles R. Everly · Baton Rouge, US
• Ronny W. Lin · Sugar Land, US
• John M. Power · Garland, US
• Steven P. Diefenbach · Baton Rouge, US
• Niomi L. Krzystowczyk · Baton Rouge, US

Key dates

• Filing date: Dec 18, 1998
• Grant date: Oct 10, 2000
• Expiry date: Dec 18, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F3/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Perfluoroaryl Grignard reagents are produced from a hydrocarbyl Grignard reagent and polyhaloaromatic compounds via separate additions of different polyhaloaromatic compounds, such that the conversion of hydrocarbyl Grignard reagent to the desired perfluoroaryl Grignard reagent is essentially complete, and thus the reaction product is free or essentially free of agents that may negatively affect subsequent reactions. The perfluoroaryl Grignard reagents may be further reacted with boron trihalides in order to obtain tris(perfluoroaryl)boranes or tetrakis(perfluoroaryl)borates.