Leukemia associated genes

US6130052A · kind A · utility

Assignee

• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB

Inventors

• Nicolas Van Baren · Brussels, BE
• Pierre Coulie · Brussels, BE
• Charles DeSmet · Raleigh, US
• Sophie Lucas · Brussels, BE
• Thierry Boon-Falleur · Brussels, BE

Key dates

• Filing date: Dec 7, 1998
• Grant date: Oct 10, 2000
• Expiry date: Dec 7, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention describes leukemia associated genes, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such genes, and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a preproTRH, tryptase-L and/or Oct-T1 gene product.