O/W emulsion composition for eye drops
US6132751A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 3, 1998 |
| Grant date | Oct 17, 2000 |
| Priority date | — |
| Expiry date | Feb 3, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0048
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An O/W emulsion composition for eye drops comprises a drug selected from the group consisting of fluorometholone, clobetasone butyrate and clobetasol propionate; a phospholipid; liquid paraffine; and water. The O/W emulsion composition is excellent in solubility of fluorometholone, clobetasone butyrate and clobetasol propionate in the tear fluid. Therefore, the composition would exhibit an anti-inflammatory activity identical to or superior to those achieved by the conventional pharmaceutical preparations, by the administration thereof at a dose lower than those for these known drugs. The composition would also be excellent from the economical standpoint and permit reduction of systemic side effects which would be encountered when the conventional drugs are instilled in the eyes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.