Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a prokinetic agent

US6132771A · kind A · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Helene Depui · Göteborg, SE
• Agneta Hallgren · Timrå, SE

Key dates

• Filing date: Feb 13, 1997
• Grant date: Oct 17, 2000
• Expiry date: Feb 13, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An oral pharmaceutical dosage form comprising a proton pump inhibitor and one or more prokinetic agents in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer. The fixed formulation is in the form of multilayered tablets, capsules or multiple unit tableted dosage forms. The multiple unit dosage forms are most preferred. The new fixed formulation is especially useful in the treatment of disorders associated with gastro oesophageal reflux diseases.