Superparamagnetic monodisperse particles
US6133047A · kind A · utility
65Cited by
20References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 15, 1998 |
| Grant date | Oct 17, 2000 |
| Priority date | — |
| Expiry date | Jan 15, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The superparamagnetic monodispersed particles comprise a core of a first polymer, an internal layer of a second polymer coating the core and in which a magnetic material is distributed, and an external layer of a third polymer coating the magnetic layer and capable of interacting with at least one biological molecule. At least the second polymer is heat sensitive and has a predetermined lower critical solubility temperature (LCST) of 15-65.degree. C. These particles may be used to isolate at least one biological molecule from a liquid specimen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.