Mono- or polyenic carboxylic acid derivatives
US6133283A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 26, 1999 |
| Grant date | Oct 17, 2000 |
| Priority date | — |
| Expiry date | Jan 26, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
To provide novel compounds relating to retinoid which can substitute for retinoic acid used for preventing and treating several diseases and having antagonism against retinoid. Heterocyclic compounds represented by the general formula (1-I) or physiologically acceptable salts thereof: EQU Z--(CR.sup.3 .dbd.CR.sup.2).sub.n --COOR.sup.1-- (1-I) Compounds represented by the general formula (2-I) or physiologically acceptable salts thereof: ##STR1## The compounds according to the present invention exhibit extremely high ability to bind RARs and are effective for treating various kind of diseases such as abnormality in cornification and rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.