Beads bound to a solid support and to nucleic acids
US6133436A · kind A · utility
492Cited by
85References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 19, 1997 |
| Grant date | Oct 17, 2000 |
| Priority date | — |
| Expiry date | Sep 19, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/1069
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are described. As compared to "flat" surfaces, beads linked to a solid support provide an increased surface area for immobilization of nucleic acids. Furthermore, by selecting a bead with the desired functionality, a practitioner can select a functionalization chemistry for immobilizing nucleic acids, which is different from the chemistry of the solid support.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.