Synthesis of bisindolylmalimides
US6133452A · kind A · utility
0Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 21, 1999 |
| Grant date | Oct 17, 2000 |
| Priority date | — |
| Expiry date | Jan 21, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is very efficient and robust macrocyclization methodology.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.