Live vaccine constituting minor risk for humans

US6136325A · kind A · utility

Assignee

• Lohmann Animal Health GmbH & Co. KG · DE

Inventors

• Klaus Linde · Grafenau, DE
• Jörg Beer · Allersberg, DE
• Bärbel Pless · Leipzig, DE

Key dates

• Filing date: Feb 19, 1997
• Grant date: Oct 24, 2000
• Expiry date: Feb 19, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A salmonella live vaccine produced from at least one attenuated immunologic live vaccine strain, characterized in that the vaccine strain has an envelope marker which results in an increased sensitivity of the vaccine strain toward a specific therapeutically effective antibiotic and has at least one chromosomal antibiotic resistance mutation for the attenuation.