Recombinant KAT enzyme and process for its preparation
US6136572A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Apr 1, 1997 |
| Grant date | Oct 24, 2000 |
| Priority date | — |
| Expiry date | Apr 1, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are isolated DNAs encoding a kynurenine aminotransferase selected from the group consisting of: (a) isolated DNA sequences which encode rat KAT; (b) an isolated DNA sequence which hybridizes to isolated DNA sequences of (a) above and which encodes a mammalian KAT enzyme; and (c) an isolated DNA sequence differing from the isolated DNA sequences of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a KAT enzyme. Vectors and host cells containing the same, oligonucleotide probes for identifying kynurenine aminotransferase, and isolated and purified kynurenine aminotransferase are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.