Aqueous acyclovir product
US6136814A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 8, 1997 |
| Grant date | Oct 24, 2000 |
| Priority date | — |
| Expiry date | Dec 8, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/1386
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a pharmaceutical product comprising an aqueous solution of acyclovir sodium contained within a sealed container constructed of an alkali resistant polymer having a CO.sub.2 permeation constant of not more than about 1.times.10.sup.-8 cc/cm.sup.2 /mm/sec/cmHg. The present invention further provides a ready-to-use aqueous acyclovir product for parenteral administration with improved shelf life. The present invention further provides a method of storing aqueous acyclovir sodium, a method of maintaining the pH of aqueous acyclovir sodium, a method of preventing the precipitation of acyclovir from aqueous acyclovir sodium, and a method of preventing the influx of CO.sub.2 in an aqueous acyclovir solution, which methods comprise storing aqueous acyclovir sodium according to the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.