Patent · US Expired

Water-soluble trioxanes as potent and safe antimalarial agents

US6136847A · kind A · utility

5Cited by
0References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 7, 1999
Grant dateOct 24, 2000
Priority date
Expiry dateApr 7, 2019

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Biologically-active, water soluble, 3-substituted trioxanes of the formula ##STR1## wherein R represents a COOH-- substituted aryl group, a substituted or unsubstituted heteroaryl group or an alkyl group, and C.sub.12 -(p-carboxy)benzyloxy trioxanes of formula ##STR2## wherein R represents a substituted or unsubstituted alkyl, alkenyl, aryl or heteroaryl group and methods for their use as antiparasitic agents, particularly for the treatment of malaria.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.