7-hexanoyltaxol and methods for preparing the same
US6136988A · kind A · utility
8Cited by
10References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 1998 |
| Grant date | Oct 24, 2000 |
| Priority date | — |
| Expiry date | Apr 10, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antitumor compound of formula (5) ##STR1## and also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2' and 7 positions of paclitaxel is followed by the hydrolysis of the 2' hexanoate group resulting in 7-hexanoyltaxol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.