Method of encapsulating biologically active agents within erythrocytes, and apparatus therefor
US6139836A · kind A · utility
24Cited by
9References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 1, 1998 |
| Grant date | Oct 31, 2000 |
| Priority date | — |
| Expiry date | May 1, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and apparatus for the encapsulation of biologically active agents in red blood cells (RBCS) is disclosed. The method is characterized in that lysed and partially lysed RBCs are concentrated prior to the introduction of the biologically active agent. The resultant carrier RBCs are stable for an extended period of time under physiological conditions and can be used for the systemic or targeted delivery of therapeutically effective amounts of one or more biologically active agents to a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.