Method and kit for predicting susceptibility to asthma
US6140047A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 12, 1998 |
| Grant date | Oct 31, 2000 |
| Priority date | — |
| Expiry date | Jan 12, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a novel method for the early prediction of a propensity to develop chronic obstructive airway disorders such as asthma. The present invention also provides kits for the early determination of the propensity to develop such a disorder. The method consists of detecting the presence of one or more alleles of an IL-1B haplotype, specifically the IL-1b (+3954) and the IL-1B (-511) loci. The presence of allele 2 at the IL-1b (+3954) locus indicates increased risk for a chronic obstructive airway disorder. The presence of allele 2 at the IL-1B (-511) locus indicates susceptibility to more severe expression of chronic obstructive airway disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.